Important

Page under development (2025-03-12)

Available implementations

This page references smart-microscopy implementations for different manufacturers and academic labs.

Academic implementations

Project overview	Repo	Institution	Contact
Automated optogenetic targeting	pertzlab/rtm-pymmcore	UNIBE	Lucien Hinderling
Outcome-driven microscopy to guide cell biology	UU-cellbiology/UU_SmartMicroscopy	UU	Alfredo Rates
Re-usable workflows on different microscope brands		EMBL-ALMF
Smart Microscopy as a Service		CCI-UG	Rafael Camacho

Industry implementations

Product overview	Repo	Brand	Contact
Inscoper’s Roboscope		Inscoper	Otmane Bouchareb
Open Application Development (OAD) in Zeiss ZEN	zeiss-microscopy/OAD	ZEISS	Philipp Seidel
ImSwitch for openUC2	openUC2/imswitch	openUC2	Benedict Diederich
	Luxendo/Acquifer-Python-API	LUXENDO	Thomas Laurent
Product overview	Repo	Brand	Contact

Hardware / Software compatibility

These tables provide a more general overview, also linking to projectes not yet represented in the working group. An overview of relevant software can also be found here: https://smartmicroscopy.org/resources/

Hardware compatibility matrix

System	Scripting support	Interfacing with external software	API	Open source compatibility	Examples provided	Behind paid-for licence
Acquifer IM	Yes	Yes	Yes	Medium	Luxendo/Acquifer-Python-API	No
Evident/Olympus (Fluoview)	Yes		Yes			Yes
Inscoper	No	Yes	Yes	High	Yes	Yes
Leica	Yes	No	No	Low	No?	Yes
Luxendo	No	Yes	No	Medium	Yes	No
Nikon	Yes	Yes	No?	Medium	Yes	Yes
UC2	Yes	Yes	Yes	High	Yes	No
Zeiss	Yes	Yes	No		Yes	Yes

Software compatibility matrix

Software	Commercial/open source	GUI or API	Interacting with other software	Custom workflows	Compatible hardware	Repo	Paper
Zeiss ZenBlue OAD	commercial
Nikon NIS-Elements Jobs module / macro language	commercial	GUI and API	no	yes	Nikon microscopes
Leica LAS-X	commercial	GUI	no	no	Leica microscopes
Inscoper	commercial	GUI and API	yes	yes	All devices supported by Inscoper
AutoMicTools package	open source
pymmcore-plus	open source	API	yes	yes	All devices with uManager drivers
Navigate	open source	GUI and API	yes	yes	All devices with uManager drivers and more		link
ImSwitch	open source					ImSwitch/ImSwitch	link
Pycro-Manager	open source	API	Integrates with Micro-Manager		All devices with uManager drivers	micro-manager/pycro-manager	link
OpenSIMView	open source				Custom built	royerlab/opensimview	link
iSpim-Control	open source
AutoScanJ	open source		Integrates with ImageJ		Leica LAS AF/X or devices with uManager drivers		link
MicroMator	open source	GUI and API	Integrates with Micro-Manager		All devices with uManager drivers	Gitlab	link